Media production

The article about transience memory is about the idea of never forgetting as a memory superpower. Dr. Richards and Frankland challenge function of forgetting. Dr. Richards and Frankland suggest that the best model of memory could be one that forgets. This was published in the Neuron and was socking as it suggested that our brains purposely forget. In a case study by Russian Neuropsychologist Luria’s patient remembered every minute of every day. This hindered the patient in his every day life. No experience was ever new.  He had trouble separating events remembering what was normal and what was new.  Some memories constantly haunted the patient in vivid details while other important facts were mixed around among st every detail of the patient’s life. Overfitting or never forgetting can cause adverse impacts on the individuals life. Richards and Frankland’s study focuses on the importance of transience in decision making. Richards and Frankland propose that transience and persistence combined is the optimal decision-making model.

Forgetting is an implicit function of memory to weed out the important memories from the fluff.  Memory is important for humans to make informed decisions based on past mistakes. In order to understand the forgetting and memory there are a few important terms. Memory is defined as making information permanent information permanent or persistence (Richards & Frankland, 2017). Transience refers to forgetting the past or petty details (Richards & Frankland, 2017).   Remembering is reactivating the patterns of nerve activity that were present at the encoding stage . Long term potentiation can explain the increase in synaptic strength between neurons. On the other hand, a depression can also increase memory. Richards and Frankland researched the enzymes necessary for transience and persistence. Intelligence is a balance of memory and transience.

The key enzymes Blake and Frankland studied were in relation to persistence were CA2 and ZIP to help encode and ensure memory In. forgetting the key enzyme is GluA2.  To start with forgetting there was research previously that promoted GluA2-containing AMPA receptor endocytosis and could also promote forgetting. Protein kinase PKC maintains Long term potentiation.  Long term potentiation was then blocked first to stimulate GluA2. Richards and Frankland also found that neurons were generated from the stem cell.  When neuron cells assimilate into the hippocampus then a memory is made. When new neurons come into the hippocampus the circuits rewrite memories.

This was then studied in rats to support the findings.  The version studied in rats was Rho GTPase Rac1 which potentiated the spines through dendric targeting. The shocks caused shrinkage. The increase in shocks caused more transient memory. In natural forgetting actin dynamics decrease forgetting. In an enriched environment neurogenesis was more likely in the hippocampus. The hippocampus is where memory is processed. Then the paper focuses on decision making since the individual has only important memories left then the individual can make informed decisions. The error to trusting in memories as they are not always remembered with reliability. Memories may be flawed but they are changed based on experience to help the individual succeed in the future. For example, maybe a person hates beef because they got very sick after eating one once. Memory helps decision making even with reliability issue.

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I further respect journalist because while trying to summarize my research article it was very difficult to decide what is important. It was also difficult to compete with the pop news article because I felt it just catered to the exciting headline instead of the actual science behind the headline. I feel in journalism it is so easy to twist the truth and miscommunicate the facts. This is because when someone else is recounting an event there is always bias to what someone feels is important. I felt the science was more important to understanding how transience memory worked. On the other hand, someone else could easily feel the overall meaning is what they want to read in a news article. I did agree with national public radio that the case study of patient S was important to understanding the concept of never forgetting.

I feel national public radio conveyed transience as if we just forget the concept of neurons was nonexistent. The news article focuses on reader interaction instead of scientific findings. Funding on the other hand runs scientific findings so public interest runs innovation either way. I included key definitions for understanding. I then followed by outlining the enzymes that caused transience and persistence of memory. I found this process very difficult as I did grossly summarize the presses of encoding and memory formation. I felt I included the science but only to a limited degree. I included the combination of transience and persistence as these were the crucial themes.The five critical questions were not clearly included in the research article therefore I could not integrate them into the media production project. The five critical questions were not addressed in the scientific study or the pop media article therefore I could not address them.


Richards, B. A., & Frankland, P. W. (2017). The Persistence and Transience of Memory. Neuron, 94(6), 1071-1084. doi:10.1016/j.neuron.2017.04.037

“Public Radio Finances.” NPR, NPR, 20 June 2013, Accessed 23 Sept. 2017.




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